Enhance similarity to human at reasonable costs.
P.A.R.I.S proposes a service of antibody chimerization. Our technology preserves the specificity and affinity of the antibody toward the antigen whereas significantly reduces the immunogenicity of the antibody in humans.
P.A.R.I.S works from any isotype and you choose the final isotype: IgA or IgG.
Do you wish to do without restraint of human serum for the calibration and positive control of your in vitro diagnostic kits?
Do you need an antibody with human heavy chain constant regions for functional testing?
P.A.R.I.S offers a service based on an exclusive technology to develop chimeric antibodies from transgenic mice.
TCR studies at P.A.R.I.S: Step by step: a timely and cost effective approach
Are you working on an antibody drug candidate? Do you need to characterized it?
Tissue Cross-Reactivity studies give key data for the development of monoclonal antibodies. They assure that the experimental antibody binds to the target site and does not bind to epitopes other than the target what could lead to treatment-related toxicity in humans.
P.A.R.I.S offers Tissue Cross-Reactivity studies, both GLP and non-GLP in support of your research or your preclinical therapeutic antibody development.
Need monoclonal antibodies? Thanks to our mAb Lab Scale packages, take advantage of in vitro quality production from only 700€ !
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